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Specialized Programs of Research Excellence (SPOREs) in Human Cancers for Years 2027, 2028, and 2029 (P50 Clinical Trial Required)

National Institutes of Health

posted

Award ceiling

—

Award floor

—

Posted

Oct 14, 2026

Closes

Sep 25, 2029

Location eligibility

No specific state restriction found in this listing — check the full opportunity for details.

Categories: Health

Eligible applicants: Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, County governments, Special district governments, For profit organizations other than small businesses, Small businesses, Private institutions of higher education, Others (see text field entitled "Additional Information on Eligibility" for clarification), Public and State controlled institutions of higher education, Native American tribal governments (Federally recognized), Independent school districts, City or township governments, State governments, Public housing authorities/Indian housing authorities, Native American tribal organizations (other than Federally recognized tribal governments), Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education

Description

Through this Notice of Funding Opportunity (NOFO), the National Cancer Institute (NCI) invites applications for P50 Research Center Grants for Specialized Programs of Research Excellence (SPOREs). Based on the proposed research, applications may be jointly funded with the National Institute of Dental and Craniofacial Research (NIDCR). This is a re-issuance of PAR-23-284. The program will fund P50 SPORE grants to support state-of-the-art investigator-initiated translational research that will contribute to improved prevention, early detection, diagnosis, and treatment of an organ-specific cancer or a highly related group of cancers. The research supported through this program must be translational and be based on human biology research using cellular, molecular, structural, biochemical, and/or genetic experimental approaches. SPORE projects must reach a translational human endpoint within the project period of the grant.

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