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INCLUDE Project: Exploratory/Developmental Research Awards for Down syndrome (R21 Clinical Trial Not Allowed)

National Institutes of Health

posted

Award ceiling

Award floor

Posted

May 12, 2026

Closes

Jun 15, 2028

Location eligibility

No specific state restriction found in this listing — check the full opportunity for details.

Categories: Health

Eligible applicants: County governments, Public housing authorities/Indian housing authorities, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, Small businesses, Native American tribal organizations (other than Federally recognized tribal governments), State governments, For profit organizations other than small businesses, Others (see text field entitled "Additional Information on Eligibility" for clarification), Private institutions of higher education, City or township governments, Special district governments, Independent school districts, Native American tribal governments (Federally recognized), Public and State controlled institutions of higher education, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education

Description

The NIH INvestigation of Co-occurring conditions across the Lifespan to Understand Down syndromE (INCLUDE) Project seeks to improve health and quality-of-life for individuals with Down syndrome. This Notice of Funding Opportunity (NOFO) invites researchers to submit applications for support of new exploratory and developmental research projects that address critical needs for Down syndrome projects, as articulated in the INCLUDE Project objectives. For example, such projects could assess the feasibility of a novel area of investigation or a new experimental system that has the potential to enhance health-related research. Another example could include the unique and innovative use of an existing methodology to explore a new scientific area. These studies may involve considerable risk but may lead to a breakthrough in a particular area, or to the development of novel techniques, agents, methodologies, models, or applications that could have a major impact on a field of biomedical, behavioral, or clinical research.

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