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BRAIN Initiative: Development and Validation of Novel Tools to Probe Cell-Specific and Circuit-Specific Processes in the Brain (R01 Clinical Trial Not Allowed)

National Institutes of Health

posted

Award ceiling

Award floor

Posted

Nov 15, 2024

Closes

Feb 8, 2027

Location eligibility

No specific state restriction found in this listing — check the full opportunity for details.

Categories: Education, Health, Income Security and Social Services

Eligible applicants: Small businesses, Nonprofits having a 501(c)(3) status with the IRS, other than institutions of higher education, Nonprofits that do not have a 501(c)(3) status with the IRS, other than institutions of higher education, For profit organizations other than small businesses, Independent school districts, Special district governments, Native American tribal governments (Federally recognized), Native American tribal organizations (other than Federally recognized tribal governments), State governments, Public housing authorities/Indian housing authorities, Public and State controlled institutions of higher education, County governments, Private institutions of higher education, City or township governments, Others (see text field entitled "Additional Information on Eligibility" for clarification)

Description

The purpose of this Brain Research through Advancing Innovative Neurotechnologies (BRAIN) Initiative is to encourage applications that will develop and validate novel tools to facilitate the detailed analysis of complex circuits and provide insights into cellular interactions that underlie brain function. The new tools and technologies should inform and/or exploit cell-type and/or circuit-level specificity. Plans for validating the utility of the tool/technology will be an essential feature of a successful application. The development of new genetic and non-genetic tools for delivering genes, proteins and chemicals to cells of interest or approaches that are expected to target specific cell types and/or circuits in the nervous system with greater precision and sensitivity than currently established methods are encouraged. Tools that can be used in a number of species/model organisms rather than those restricted to a single species are highly desired. Applications that provide approaches that break through existing technical barriers to substantially improve current capabilities are highly encouraged.

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